• PLASMA ACTH (ACTH) In Jaipur

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 ACTH is a hormone produced by the pituitary gland in the brain. It plays a crucial role in the regulation of cortisol production by the adrenal glands.

ACTH secretion is controlled by a complex feedback loop involving the hypothalamus, pituitary gland, and adrenal glands. Elevated plasma ACTH levels can indicate various conditions, including:

1. Adrenal insufficiency: In conditions such as primary adrenal insufficiency (Addison's disease) or secondary adrenal insufficiency, in which there is inadequate production of cortisol, plasma ACTH levels are often elevated as the body tries to stimulate the adrenal glands to produce more cortisol.

2. Pituitary tumors: Certain pituitary tumors, such as corticotroph adenomas, can cause excessive production of ACTH, leading to abnormally high levels of ACTH in the blood. This, in turn, can result in excessive cortisol production (Cushing's syndrome).

3. Ectopic ACTH production: In some cases, non-pituitary tumors, such as lung cancers, pancreatic tumors, or carcinoid tumors, can produce ACTH. This leads to increased levels of ACTH in the blood, causing excessive cortisol secretion.

4. Stress and hypothalamic-pituitary axis dysfunction: Physical or emotional stress can temporarily elevate plasma ACTH levels. There may also be abnormalities in the hypothalamic-pituitary axis, which can affect ACTH production and regulation.

Measuring plasma ACTH levels can be helpful in diagnosing and monitoring conditions related to abnormal cortisol production or adrenal insufficiency. It is commonly carried out in conjunction with other tests, such as cortisol level measurements, imaging studies, and clinical evaluations, to establish a comprehensive diagnosis.

Interpretation of plasma ACTH levels should be done in consultation with a healthcare provider familiar with the individual's medical history and clinical presentation.

  • What is a CRP Test?

    "The protein C-reactive protein (CRP) is produced by the liver. When a disorder causes inflammation anywhere in the body, CRP levels in the blood rise. A CRP test detects inflammation caused by acute illnesses or monitors the degree of illness in chronic circumstances by measuring the level of CRP in the blood."

  • What is CRP Test normal range?

    "A normal CRP value is less than 10 milligrams per liter (mg/L) in a routine test. A CRP level of more than 10 mg/L indicates a significant illness, trauma, or chronic illness, and will almost certainly need further tests to ascertain the reason."

  • What infections cause high CRP?

    "The most common infections that can cause elevated levels of CRP are Sepsis and other bacterial infections, Various types of fungal infections, Inflammation and bleeding of the intestines, Inflammatory bowel disease, Lupus, Rheumatoid Arthritis (RA), Osteomyelitis which causes infection of the bone."

PLASMA ACTH

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