The Activated Partial Thromboplastin Time (aPTT) also known as partial thromboplastin time (PTT) is a screening test that helps evaluate a person?s ability to form blood clots appropriately. This test is performed to detect bleeding and clotting disorders and to monitor the treatment with blood-thinning medicines. In case of unexplained bleeding, inappropriate blood clotting, or recurrent miscarriages and sometimes before a scheduled surgery aPTT test is performed. This test is usually performed with other tests like prothrombin time and thrombin time to measure the clotting time accurately. Values greater than normal, could be due to bleeding disorder or liver disease. Values less than normal indicate that you may have a higher chance of getting blood clots and several miscarriages.
In the PTTK test, a blood sample is mixed with a reagent called kaolin, which initiates the clotting process. The time it takes for the blood to form a clot is measured. The PTTK test specifically evaluates the effectiveness of the intrinsic pathway by excluding the extrinsic pathway.
The intrinsic pathway involves several clotting factors, including factors XII, XI, IX, VIII, and X, which work together to form blood clots. Any abnormality or deficiency in these factors can lead to a prolonged PTTK result.
The PTTK test is often used to diagnose or monitor various bleeding disorders, such as hemophilia and von Willebrand disease, which are characterized by deficiencies in specific clotting factors. It can also be used to monitor anticoagulant therapy with medications like heparin.
The results of the PTTK test are typically reported as the time it takes for the blood to clot, compared to a reference range provided by the laboratory. A prolonged PTTK may indicate a clotting factor deficiency or dysfunction, while a normal result suggests normal clotting function.
It's important to note that the PTTK test is just one component of a comprehensive coagulation
Report Time:
24 Hours
Fasting Time:
Free
Recommended Test:
Male, Female
Recommended age:
5-99 Years
Book on our website or app, or request a Health Advisor callback.
Health Advisor & medical advisor provide guidance of testing process.
Enjoy free sample collection at home or office by expert phlebotomists.
Your sample is transported, processed, and verified by our expert team.
Receive AI-based Smart Reports with free consultations.