This test helps in measuring the level of complement 3 and 4 proteins which are a part of complement system. This system works with the immune system and the abnormal level of these proteins is an indication of autoimmune disorders. It is used to diagnose autoimmune diseases such as lupus and rheumatoid arthritis. You may need this test if you have symptoms such as rashes, fatigue, mouth sores, hair loss, chest pain, joint pain, and fever. The test is also used to check the treatment efficacy of lupus or other autoimmune disorder.
The complement system helps to identify and eliminate foreign substances, such as bacteria and viruses, from the body.
Complement C3 is a central component of the complement system. It is synthesized in the liver and is involved in various immune functions. When complement C3 is activated, it can trigger a cascade of reactions that lead to the destruction of pathogens, promotion of inflammation, and recruitment of immune cells to the site of infection.
Complement C4 is another important component of the complement system. It is also produced in the liver and has multiple functions in the immune response. Like complement C3, complement C4 can initiate the activation of the complement cascade, leading to pathogen destruction and immune cell recruitment. Additionally, complement C4 is involved in the clearance of immune complexes from the bloodstream.
Measurements of complement C3 and C4 levels can be useful in diagnosing and monitoring certain autoimmune diseases, such as systemic lupus erythematosus (SLE), that involve abnormal activation of the complement system. In SLE, decreased levels of complement C3 and C4 may indicate complement system activation and consumption.
However, it is important to note that complement C3 and C4 levels alone are not definitive in diagnosing specific diseases and should be interpreted in conjunction with other clinical findings. It is always recommended to consult with a healthcare professional for accurate assessment and interpretation of complement C3 and C4 levels.
Report Time:
24 Hours
Fasting Time:
Free
Recommended Test:
Male, Female
Recommended age:
5-99 Years
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