A 45 year old gentleman presented wth abdominal pain and colonoscopy report that screamed “ suspicious ulcer in the caecum.” The endoscopist whispered “ malignancy?” - and the pathologist quietly whispered back, “let’s see who’s really living rent free in there.”
Punch biopsy landed. Histology revealed ulcerated mucosa, necrosis and surprise guest star - trophozoites of entamoeba history Tisca indulging in reythrophagocytosis like fine dinning critics 🍷🍽️
No dysplasia, no tumour - just parasitic is chief! Turns out, the “ malignant ulcer” was simply an a amoeba having a messy lunch date with colonic tissue.
🧠🧠Take home message :
Not every cecal ulcer is a carcinoma in disguise - sometimes it’s just amebiasis with an attitude. Before sending the patient down the oncology lane, remember: a little anti- amoebic therapy can sometimes do what chemotherapy never should.

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